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It has been proposed that D-serine and glutamate combine to activate NMDA receptors. The atypical feature of D-serine is that it resides in the glia (the supporting cells surrounding neurons), rather than in neurons. Another proposed novel neurotransmitter is adenosine, which has neuroactive properties, yet is neither a biogenic amine nor an amino acid. ” This means that organisms, organ systems, tissues, or individual cells, to assure survival, may alter their functioning (chemical functioning and even structure/morphology) to accommodate to changing environmental circumstances.

Sexual dysfunction, which can translate into interpersonal problems in intimate relationships.  Bizarre behavior enacted during a manic or a psychotic episode. Such behavior can continue to be a source of tremendous personal embarrassment and shame long after the psychotic episode is resolved. These consequences of a primarily biologically based mental disorder have an impact on the individual’s sense of self-worth and competency in the world. Conversely, this increased level of despair can, in itself, operate to intensify the u ­ nderlying ­biological abnormality.

Because of this influence on adjacent neurons, neurotransmitters are sometimes referred to as first messenger molecules. , away from the cell body) ending in the terminal bouton. Here, the impulse causes the release of neurotransmitter molecules into the tiny space between nerve cells referred to as the synapse. The human brain’s 100 billion nerve cells are richly inter­ connected, making approximately 100 trillion synapses. Yet in almost all instances, the nerve cells do not actually touch one another; they are separated by this tiny space.

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